Article Open access Published: 18 September 2026

Clinical Pharmacist Collaborative Drug Therapy Management in Resistant Hypertension: A Randomized Trial in Primary Care

Dr. Sarah E. Henderson, PharmD; Marcus L. Vance, MD; Alistair Thorne, PhD

Abstract

Apparent treatment-resistant hypertension affects 12-15% of hypertensive adults. We conducted a pragmatic RCT across 16 primary care clinics assessing pharmacist-physician collaborative drug therapy management compared to usual care over 6 months.